What are the first signs and symptoms of LAMA2-RD?

Early signs may include hypotonia (low muscle tone, meaning the baby feels limp or ‘floppy’), poor head control, reduced movement in the womb or after birth, delayed motor milestones (such as sitting later than expected), feeding difficulties, dysphagia (difficulty swallowing) and breathing problems. In the milder forms of LAMA2-RD, early signs may be subtle and only noticed later in childhood or adulthood.