What does the laminin alpha-2 protein do in the body?

Laminin alpha-2 is a protein that acts like a glue between muscle cells and the tissue surrounding them. The protein is like the mortar between bricks in a wall, it holds everything together and keeps the structure stable. In LAMA2-RD patients, who have little or no functioning laminin alpha-2 protein (mortar), the muscle cells (bricks) lose their grip, become fragile, weaken and gradually break down. This is why muscles weaken over time in LAMA2-RD. You can find more explanations here.

What is LAMA2-RD? What does LAMA2 stand for? What causes LAMA2-RD? What is the role of the LAMA2 gene? What is the difference between LAMA2-RD, MDC1A, merosin-deficient congenital muscular dystrophy and LAMA2-CMD? Is LAMA2-RD a muscle disease? How rare is LAMA2-RD? How many people worldwide are living with LAMA2-RD? How many patients are there in Europe? How many LAMA2-RD patients are there in my country? What forms of LAMA2-RD exist? What is the difference between the severe and milder forms of LAMA2-RD? Is LAMA2-RD inherited? Can two healthy parents have a child with LAMA2-RD? What is the chance that another child in our family will have LAMA2-RD? Is prenatal testing available for LAMA2-RD? Is preimplantation genetic testing possible? What is the difference between the LAMA2 gene and the laminin alpha-2 protein

What does the laminin alpha-2 protein do in the body?

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